The European Industry sector is one of the EU economy pillars accounting for ‘2 million enterprises, 33 million jobs and 60% of productivity growth’. However only 6% of the ecosystem seems to be fully digitized. The importance to respond to the emerging market challenges and it faster needs, to adapt the entire production process to the new scenarios to become cost-effective and productive, the obstacles to reduce the competence gap among other key challenges must be placed at the heart of a full deployment of a Digital Factory Strategy to gain chances for future competitive success. The discussion will be focused on how to stepping into the path of transformation towards a fully integrated factory and what the benefits and the risks of a real time ecosystem with both suppliers and customers will imply.