Medical research and technology advances and health systems’ sustainability pressures are driving the need for more personalized and integrated patient services. Patient value in terms of clinical outcomes and experience become the most important KPI for healthcare and life sciences organizations and the main DX driver. Enabling a Patient of One vision calls for an intelligent 360° view of the patient/customer. A radical transformation of the information management approach is essential for enabling the new health intelligent core, and will create an efficient patient led network of services and relationships. This presentation will analyze how most advanced organization are addressing the key barriers to this patient value led digital transformation, devising a strategy that is helping them to move from digital distraction to digital determination.